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Product name: Boc Anhydride
Synonyms: Di-tert-butyl pyrocarbonate, Dicarbonic acid bis(1, 1-dimethylethyl)ester, Pyrocarbonic acid di-tert-butyl ester, BOC-anhydride.
Description of Boc Anhydride:
Di-tert-butyl dicarbonate is a reagent widely used in organic synthesis. This carbonate ester reacts with amines to give N-tert-butoxycarbonyl or so-called t-BOC derivatives. These derivatives do not behave as amines, which allows certain subsequent transformations to occur that would have otherwise affected the amine functional group. The t-BOC can later be removed from the amine using acids. Thus, t-BOC serves as a protective group, for instance in solid phase peptide synthesis. It is unreactive to most bases and nucleophiles, allowing for an orthogonal Fmoc protection.
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